Benzinga's Top #PreMarket Losers

Horizon Pharma PLC HZNP shares declined 20.24 percent to $17.90 in pre-market trading. Horizon Pharma responded to a lawsuit filed by Express Scripts Holding Company ESRX and recent allegations. Depomed Inc DEPO shares fell 5.70 percent to $20.00 in pre-market trading after gaining 5.47 percent on Tuesday. Macy's, Inc. M shares tumbled 5.45 percent to $44.44 in pre-market trading after the company lowered its full-year earnings forecast and rejected the REIT formation. AmTrust Financial Services Inc AFSI shares dipped 5.06 percent to $63.20 in pre-market trading after the company commenced an underwritten public offering of 5 million of its common stock. Premier Inc PINC fell 1.90 percent to $35.05 in pre-market trading after the company priced 4.033 million share offering at $34.50 per share.