Benzinga's Top #PreMarket Losers

Nektar Therapeutics NKTR shares fell 16.50% to $11.80 in pre-market trading after the company said its breast cancer treatment failed to produce significant results for the primary end point in a Phase III trial. RSP Permian Inc RSPP fell 5.43% to $25.60 in pre-market trading after the company announced the pricing of public offering of 5 million shares by the company and 4 million shares by certain selling stockholders. Adobe Systems Incorporated ADBE shares declined 4.53% to $76.05 in pre-market trading. Adobe reported better-than-expected results for the fiscal first quarter. Anthera Pharmaceuticals Inc ANTH shares dropped 4.41% to $4.55 in pre-market after the company announced a stock offering of undetermined size to raise capital for research and development. The company said Monday it will continue a Phase III trial of its kidney disease treatment. BioScrip, Inc. BIOS slipped 3.49% to $4.43 in pre-market trading after rising 7.24% on Tuesday.