Benzinga's Top #PreMarket Losers

Clovis Oncology Inc CLVS shares dropped 8.59 percent to $84.50 in pre-market after the company reported updated Phase 2 results from two ongoing clinical studies with rucaparib: ARIEL2 and Study 10. Express Scripts Holding Company ESRX shares declined 1.14 percent to $86.15 in pre-market trading. Raymond James downgraded Express Scripts Holding from Outperform to Market Perform. F5 Networks, Inc. FFIV fell 0.88 percent to $124.59 in pre-market trading. Citigroup downgraded F5 Networks from Buy to Neutral and raised the price target from $122.00 to $132.00. Vodafone Group Plc (ADR) VOD shares fell 0.87 percent to $38.69 in pre-market trading after dropping 0.38 percent on Friday. Williams Companies Inc WMB shares tumbled 0.65 percent to $50.77 in pre-market trading after falling 0.35 percent on Friday.