Benzinga's Top #PreMarket Losers

Shire PLC (ADR) SHPG shares declined 2.68 percent to $244.77 in pre-market trading. Shire has approached Swiss drug company Actelion Ltd ALIOF regarding a potential £12 billion buyout, according to sources as reported by the UK's Sunday Times. American Airlines Group Inc AAL shares fell 1.61 percent to $41.05 in pre-market trading after dropping 1.07 percent on Friday. Visa Inc V fell 0.91 percent to $67.76 in pre-market trading after gaining 0.25 percent on Friday. Delta Air Lines, Inc. DAL shares tumbled 0.82 percent to $42.55 in pre-market trading. Analysts at Raymond James downgraded Delta Air Lines from Strong Buy to Outperform. Micron Technology, Inc. MU shares dropped 0.38 percent to $26.49 in pre-market after declining 1.46 percent on Friday.