Gainers

  • GlycoMimetics Inc GLYC shares rose 35 percent to $7.25 in pre-market trading as the company reported that GMI-1271 has received the FDA Breakthrough therapy designation for adult relapsed/refractory acute myeloid leukemia.
  • Affimed NV AFMD shares rose 22.2 percent to $2.75 in the pre-market trading session. Affimed reported that it will present immune cell engager data at the American Society of Clinical Oncology Annual Meeting and EACR-AACR-SIC Special Conference.
  • CytRx Corporation CYTX rose 19.1 percent to $0.540 in pre-market trading. CytRx will present global Phase 3 aldoxorubicin clinical data in patients with soft tissue sarcomas at the 2017 ASCO Annual Meeting.
  • Syndax Pharmaceuticals Inc SNDX shares rose 10.5 percent to $15.00 in pre-market trading after surging 44.62 percent on Wednesday. Syndax issued results from Phase 2 ENCORE 601 trial of entinostat in combo with Merck's KEYTRUDA for the treatment of advanced melanoma.
  • xG Technology Inc XGTI rose 9.7 percent to $2.04 in pre-market trading after declining 7.92 percent on Wednesday.
  • Pandora Media Inc P rose 8.7 percent to $9.71 in pre-market trading. Sirius XM Holdings Inc. SIRI is in talks about bidding for Pandora, according to sources as reported by the New York Post.
  • Incyte Corporation INCY rose 7.9 percent to $130.00 in pre-market trading. Incyte disclosed that its IDO1 enzyme inhibitor in combo with Merck's anti-PD-1 therapy is 'well-tolerated and demonstrated durable clinical responses across multiple solid tumors'. The company also announced that first data from combo of epacadostat with Bristol-Myers' opdivo showed that combo is 'well-tolerated and demonstrates promising clinical outcomes in multiple advanced solid tumors.'
  • Shire PLC (ADR) SHPG rose 7.3 percent to $195.50 in pre-market trading after the company disclosed that its lanadelumab study met primary endpoint.
  • Janus Capital Group Inc JNS rose 7.2 percent to $14.85 in pre-market trading after declining 3.01 percent on Wednesday.
  • Childrens Place Inc PLCE rose 6.6 percent to $119.00 in pre-market trading after the company posted upbeat quarterly profit.
  • Ralph Lauren Corp RL shares rose 5.2 percent to $76.50 in pre-market trading after the company posted upbeat quarterly profit.
  • L Brands Inc LB rose 5 percent to $50.81 in pre-market trading after the company reported upbeat earnings for its first quarter and raised its FY17 outlook.

Inventure Foods Inc SNAK shares rose 5 percent to $4.26 in pre-market trading after dropping 2.17 percent on Wednesday.


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Losers

  • Petroleo Brasileiro SA Petrobras (ADR) PBR fell 15 percent to $8.75 in pre-market trading. Petrobras CEO said that the company will pay first dividend since 2014, if it earns profit in 2017, Reuters reported.
  • Itau Unibanco Holding SA (ADR) ITUB fell 14.7 percent to $10.69 in pre-market trading after dipping 3.28 percent on Wednesday.
  • Gerdau SA (ADR) GGB fell 14.7 percent to $2.72 in pre-market trading after declining 3.19 percent on Wednesday.
  • Banco Bradesco SA (ADR) BBD shares fell 13.3 percent to $8.70 in the pre-market trading session after dropping 3.09 percent on Wednesday.
  • Workhorse Group Inc WKHS fell 9.6 percent to $3.00 in pre-market trading after rising 4.73 percent on Wednesday.
  • Vale SA (ADR) VALE fell 9.3 percent to $7.75 in pre-market trading after dropping 2.62 percent on Wednesday.
  • ZTO Express (Cayman) Inc (ADR) ZTO shares fell 7.4 percent to $13.01 in pre-market trading. ZTO reported Q1 adjusted earnings of $0.10 per share on sales of $379.9 million. The company also named Hongqun Hu as COO.
  • Cisco Systems, Inc. CSCO shares fell 7.2 percent to $31.40 in pre-market trading. Cisco reported better-than-expected earnings for its third quarter, but issued a weak revenue forecast for the current quarter. Cisco also announced plans to cut an additional 1,100 jobs.
  • BioCryst Pharmaceuticals, Inc. BCRX fell 6.5 percent to $5.20 in pre-market trading after dropping 4.30 percent on Wednesday.
  • Stratasys, Ltd. SSYS fell 6.1 percent to $26.10 in pre-market trading. Jefferies downgraded Stratasys from Buy to Hold.
  • BlackBerry Ltd BBRY fell 5 percent to $9.60 in pre-market trading after slipping 0.79 percent on Wednesday.
  • Melco Resorts & Entertainment Ltd(ADR) MLCO fell around 4.1 percent to $20.39 in pre-market trading after dropping 6.26 percent on Wednesday.
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