Gainers

  • DelMar Pharmaceuticals Inc DMPI rose 46.5 percent to $1.64 in pre-market trading after announcing issuance of new patent for VAL-08.
  • Alnylam Pharmaceuticals, Inc. ALNY rose 21.9 percent to $91.50 in pre-market trading following positive APOLLO 3 results.
  • ProQR Therapeutics NV PRQR rose 12 percent to $5.60 in pre-market trading after tumbling 15.97 percent on Tuesday.
  • Karyopharm Therapeutics Inc KPTI shares rose 9.3 percent to $11.50 in the pre-market trading session after the company reported that SEAL study's primary endpoint of progression-free survival showed superiority over placebo.
  • ON Semiconductor Corp ON shares rose 9.1 percent to $19.21 in pre-market trading after gaining 0.92 percent on Tuesday.
  • AVEO Pharmaceuticals, Inc. AVEO rose 8.9 percent to $4.18 in pre-market trading. AVEO Oncology and EUSA Pharma disclosed that EUSA Pharma has opted into the Phase 1/2 TiNivo study.
  • Aluminum Corp. of China Limited (ADR) ACH rose 6.8 percent to $22.75 in pre-market trading after gaining 1.33 percent on Tuesday.
  • Imax Corp (USA) IMAX shares rose 4.8 percent to $23.05 in pre-market trading after falling 0.68 percent on Tuesday.
  • Golden Ocean Group Ltd GOGL rose 4.7 percent to $9.20 in pre-market trading. After gaining 0.23 percent on Tuesday.
  • Mattel, Inc. MAT rose 4.2 percent to $15.68 in pre-market trading after gaining 1.21 percent on Tuesday.
  • Sibanye Gold Ltd (ADR) SBGL shares rose 3.3 percent to $4.99 in pre-market trading after dropping 8.70 percent on Tuesday.
  • Fitbit Inc FIT rose 3.1 percent to $6.43 in pre-market trading after declining 4.88 percent on Tuesday.
  • Melco Resorts & Entertainment Ltd(ADR) MLCO rose 2.8 percent to $24.45 in pre-market trading after climbing 3.35 percent on Tuesday.
  • Fang Holdings Ltd SFUN rose 2.6 percent to $4.40 in pre-market trading after falling 0.46 percent on Tuesday.


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Losers

  • Bed Bath & Beyond Inc. BBBY shares fell 14.6 percent to $23.10 in pre-market trading as the company reported downbeat earnings for its third quarter.
  • Ionis Pharmaceuticals Inc IONS shares fell 8.6 percent to $54.00 in pre-market trading amid positive news related to Alnylam's RNAi drug.
  • LM Funding America, Inc. LMFA fell 7.8 percent to $2.36 in pre-market trading after declining 9.86 percent on Tuesday.
  • Sasol Limited (ADR) SSL fell 7 percent to $27.98 in pre-market trading after rising 0.40 percent on Tuesday.
  • MAG Silver Corp (USA) MAG shares fell 5.2 percent to $11.34 in pre-market trading after gaining 1.61 percent on Tuesday.
  • CGG SA (ADR) CGG fell 4.9 percent to $5.50 in pre-market trading after declining 3.18 percent on Tuesday.
  • Capricor Therapeutics Inc CAPR fell 4.5 percent to $2.15 in pre-market trading after surging 70.45 percent on Tuesday.
  • General Mills, Inc. GIS shares fell 4.3 percent to $53.00 after the company reported weaker-than-expected earnings for its first quarter.
  • Bank of New York Mellon Corp BK shares fell 4 percent to $50.00 in pre-market trading after rising 0.66 percent on Tuesday.
  • Western Digital Corp WDC fell 4.1 percent to $86.23 in pre-market trading. Toshiba's board has selected Bain Group to acquire memory chip business, Reuters reported.
  • Mobil'nye Telesistemy PAO (ADR) MBT fell 3.3 percent to $10.50 in pre-market trading after rising 3.24 percent on Tuesday.
  • Dynavax Technologies Corporation DVAX shares fell 3.2 percent to $20.20 in pre-market trading after gaining 0.48 percent on Tuesday.
  • Nabriva Therapeutics plc NBRV fell 3.1 percent to $8.91. Nabriva Therapeutics priced its 9.41 million share offering at $8.50 per share.
  • Adobe Systems Incorporated ADBE fell 2.8 percent to $152.25 in pre-market trading. Adobe posted upbeat earnings for its third quarter on Tuesday.
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