Gainers
- Spark Therapeutics, Inc. ONCE shares climbed 120.09 percent to close at $113.48 on Monday after Roche Holdings AG RHHBY announced plans to acquire the company for $114.50 per share in cash.
- Clementia Pharmaceuticals Inc. CMTA gained 74.66 percent to close at $26.06 after the company announced that Ipsen would acquire the company for $25 per share in cash and up to an additional $6 per share depending on FDA acceptance of a new drug application for palovarotene.
- Planet Green Holdings Corp. PLAG gained 4.197 percent to close at $4.2875.
- Uniqure NV QURE shares rose 34.3 percent to close at $55.87. Cantor Fitzgerald maintained uniQure with an Overweight and raised the price target from $68 to $81. Shares of gene therapy companies are trading higher after Roche announced it would acquire Spark Therapeutics for $114.50 per share in cash.
- Phoenix New Media Limited FENG climbed 31.94 percent to close at $4.75 after announcing a letter of intent to sell a 32 percent stake in Particle for $448 million in cash. The company also reported a strategic investment in Tadu.
- Titan Pharmaceuticals, Inc. TTNP shares rose 30.5 percent to close at $1.84 after the company reported a partnership with AllianceRx Walgreens to expand patient access to Probuphine.
- China SXT Pharmaceuticals, Inc. SXTC gained 25.45 percent to close at $6.31.
- CRISPR Therapeutics AG CRSP shares rose 25.2 percent to close at $39.65. CRISPR Therapeutics posted Q4 loss of $0.92 per share on sales of $115,000. CRISPR Therapeutics and Vertex Pharmaceuticals disclosed that the first patient has been enrolled in a Phase 1/2 clinical study of CTX001 in severe SCD in the U.S. and is expected to be infused with CTX001 in mid-2019.
- X Financial XYF gained 23.99 percent to close at $7.08.
- Libbey Inc. LBY shares rose 23.88 percent to close at $4.41.
- AVROBIO, Inc. AVRO surged 21.63 percent to close at $16.98 on Monday.
- Veritone, Inc. VERI shares jumped 20.45 percent to close at $6.36.
- Stamps.com Inc. STMP climbed 18.61 percent to close at $99.22 on a buy-the-dip rebound following a 50%+ decline on Friday.
- SPI Energy Co., Ltd. SPI gained 17.15 percent to close at $2.80.
- Akcea Therapeutics, Inc. AKCA surged 16.72 percent to close at $31.91 after the company announced Novartis licensed AKCEA-APO(a)-LRx; Akcea is set to receive a $150 million licensing fee that will be split with Ionis equally.
- Hexindai Inc. HX shares gained 16.42 percent to close at $3.97.
- Aurinia Pharmaceuticals Inc. AUPH rose 16.32 percent to close at $7.20 on Monday after the company received a notice of allowance from the US Patent and Trademark Office for claims directed to its novel voclosporin dosing protocol.
- Adverum Biotechnologies, Inc. ADVM gained 16.22 percent to close at $4.3000.
- REGENXBIO Inc. RGNX gained 16.17 percent to close at $54.02.
- Oasmia Pharmaceutical AB (publ) OASM gained 15.28 percent to close at $2.8184.
- Neurotrope, Inc. NTRP shares rose 14.89 percent to close at $5.17.
- Uniti Group Inc. UNIT shares surged 14.84 percent to close at $10.60.
- Ocular Therapeutix, Inc. OCUL gained 14.66 percent to close at $4.7700.
- bluebird bio, Inc. BLUE shares gained 14.16 percent to close at $149.91 in sympathy with Roche's acquisition of Spark Therapeutics earlier Monday.
- Mmtec, Inc. MTC shares gained 13.4 percent to close at $5.50.
- PPDAI Group Inc. PPDF rose 13.32 percent to close at $5.02.
- Abeona Therapeutics Inc. ABEO surged 13.29 percent to close at $7.33.
- Constellation Pharmaceuticals, Inc. CNST gained 13.14 percent to close at $10.76.
- Cerecor Inc. CERC climbed 13.06 percent to close at $6.06.
- Fuwei Films (Holdings) Co., Ltd. FFHL rose 12.98 percent to close at $2.35.
- Fate Therapeutics, Inc. FATE gained 12.83 percent to close at $16.27 on Monday.
- MeiraGTx Holdings plc MGTX shares jumped 12.54 percent to close at $14.36.
- Zosano Pharma Corporation ZSAN gained 12.11 percent to close at $5.09.
- Magenta Therapeutics, Inc. MGTA surged 12.03 percent to close at $10.52.
- Nightstar Therapeutics plc NITE rose 11.98 percent to close at $15.89.
- StoneCo Ltd. STNE shares gained 11.77 percent to close at $29.35 on Monday.
- Rocket Pharmaceuticals, Inc. RCKT climbed 11.63 percent to close at $16.61.
- Homology Medicines, Inc. FIXX gained 11.47 percent to close at $27.02.
- Audentes Therapeutics, Inc. BOLD shares rose 11.38 percent to close at $29.26 in sympathy to Roche's acquisition of Spark Therapeutics and an upgrade from Neutral to Buy from Chardan Capital.
- Anaplan, Inc. PLAN gained 10.3 percent to close at $36.83 after reporting Q4 results.
- Orchard Therapeutics plc ORTX shares climbed 9.77 percent to close at $17.52.
- Solid Biosciences Inc. SLDB rose 9.6 percent to close at $9.82.
- Danaher Corporation DHR gained 8.52 percent to close at $123.15 after the company announced it would buy General Electric's Life Sciences business for $21.4 billion and that the acquisition would be accretive to adjusted earnings.
- Summit Wireless Technologies, Inc. WISA shares rose 8.23 percent to close at $2.50.
- Carter's, Inc. CRI rose 8.12 percent to close at $100.03 following upbeat Q4 results.
- Wayfair Inc W gained 6.89 percent to close at $160.28 after multiple banks reiterated the company's stock with positive ratings following a strong Q4 earnings beat.
- Westinghouse Air Brake Technologies Corp WAB gained 6.41 percent to close at $78.06 following Q4 results.
- General Electric Company GE shares gained 6.39 percent to close at $10.82 after the company agreed to sell its BioPharma business to Danaher Corporation DHR for $21.4 billion.
- Amicus Therapeutics, Inc. FOLD gained 5.87 percent to close at $12.44 after the FDA granted breakthrough therapy designation to the company's AT-GAA.
- Jianpu Technology Inc. JT rose 5.83 percent to close at $6.54 after reporting upbeat Q4 results.
- Voyager Therapeutics, Inc. VYGR rose 5.64 percent to close at $13.86 on Monday after surging 22.85 percent on Friday.
- Editas Medicine, Inc. EDIT rose 5.33 percent to close at $20.93.
Losers
- Windstream Holdings, Inc. WIN shares dipped 46.89 percent to close at $0.4530 on rumors of the company declaring bankruptcy.
- Achieve Life Sciences, Inc. ACHV shares tumbled 19.7 percent to close at $2.65 on Monday after rising 82.32 percent on Friday.
- Synergy Pharmaceuticals Inc. SGYP shares declined 17.21 percent to close at $0.2401 following late-Friday Dow Jones report that the companywon court permission to draw down remainder of a $155 million bankruptcy financing package.
- Sunlands Online Education Group STG shares fell 17.18 percent to close at $4.05.
- Travelzoo TZOO dipped 14.12 percent to close at $12.71.
- Harpoon Therapeutics, Inc. HARP shares fell 14.06 percent to close at $14.36.
- Tyme Technologies, Inc. TYME dropped 12.37 percent to close at $2.62.
- eHealth, Inc. EHTH dropped 11.36 percent to close at $56.25.
- Ramaco Resources, Inc. METC fell 10.64 percent to close at $5.29 after reporting preliminary 2018 results.
- Dorman Products Inc. DORM declined 10.42 percent to close at $81.27 after the company issued weak FY19 earnings forecast.
- Textainer Group Holdings Limited TGH dipped 10.38 percent to close at $11.40.
- Research Frontiers Incorporated REFR tumbled 9.83 percent to close at $2.11 on Monday.
- Overstock.com, Inc. OSTK dropped 9.2 percent to close at $18.06.
- Riot Blockchain, Inc. RIOT shares declined 9.11 percent to close at $3.59.
- Melinta Therapeutics, Inc. MLNT shares dropped 9.02 percent to close at $5.95.
- Blink Charging Co. BLNK shares tumbled 8.83 percent to close at $3.20.
- Kandi Technologies Group, Inc. KNDI dropped 8.54 percent to close at $8.25.
- Cronos Group Inc CRON fell 7.62 percent to close at $20.25. Analysts at Jefferies initiated coverage on Cronos with an Underperform rating.
- B.O.S Better Online Solutions Ltd. BOSC shares fell 5.4 percent to close at $3.33. BOS Better Online Solutions posted Q4 earnings of $0.11 per share on sales of $9.1 million.
- OncoCyte Corporation OCX fell 5.19 percent to close at $3.47 after declining 8.50 percent on Friday.
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