The latest price target for Septerna (NASDAQ:SEPN) was reported by HC Wainwright & Co. on April 14, 2026. The analyst firm set a price target for $40.00 expecting SEPN to rise to within 12 months (a possible 58.96% upside). 16 analyst firms have reported ratings in the last year.

The latest analyst rating for Septerna (NASDAQ:SEPN) was provided by HC Wainwright & Co., and Septerna reiterated their buy rating.

The last upgrade for Septerna Inc happened on November 14, 2025 when Wells Fargo raised their price target to $28. Wells Fargo previously had an equal-weight for Septerna Inc.

The last downgrade for Septerna Inc happened on February 18, 2025 when Wells Fargo changed their price target from $43 to $14 for Septerna Inc.

Analysts arrive at stock ratings after doing extensive research, which includes going through public financial statements, talking to executives and customers of Septerna, and listening in to earnings conference calls. Most analysts do this every three months, so you should get 4 ratings per company per firm each year. The last rating for Septerna was filed on April 14, 2026 so you should expect the next rating to be made available sometime around April 14, 2027.

While ratings are subjective and will change, the latest Septerna (SEPN) rating was a reiterated with a price target of $40.00 to $40.00. The current price Septerna (SEPN) is trading at is $25.16, which is out of the analyst’s predicted range.