Short interest in Spyre Therapeutics Inc (NASDAQ:SYRE) increased during the last reporting period, rising from 4.84M to 7.79M. This put 18.56% of the company's publicly available shares short.

Short interest for Spyre Therapeutics gives investors a sense of the degree to which investors are betting on the decline of Spyre Therapeutics's stock. Short interest data is updated every two weeks.

Based on the recent average volume of 1.81M shares traded per day, it would take 4.3 day(s) for holders of this short interest to close out their positions without sending the stock sharply higher.