40 Stocks Moving in Wednesday's Pre-Market Session

Gainers

• Caladrius Biosciences, Inc. CLBS rose 132.4% to $3.79 in pre-market trading. Caladrius Biosciences said it treated first patient in Phase 2b FREEDOM trial of CLBS16 for the treatment of coronary microvascular dysfunction.
• Steel Connect, Inc. STCN rose 79% to $1.95 in pre-market trading after climbing over 36% on Tuesday.
• Lineage Cell Therapeutics, Inc. LCTX shares rose 62% to $4.00 in pre-market trading after jumping over 14% on Tuesday.
• Daré Bioscience, Inc.. DARE shares rose 56.9% to $3.70 in pre-market trading after climbing around 64% on Tuesday. Dare Bioscience, earlier during the month, filed for offer and sale of up to 6.4 million shares of common stock by Lincoln Park Capital Fund.
• ENDRA Life Sciences Inc. NDRA shares rose 43.7% to $2.50 in pre-market trading after jumping over 65% on Tuesday. ENDRA Life Sciences, last week, was granted 13th US patent for its Taeus platform technology.
• Inuvo, Inc.. INUV rose 36.6% to $1.98 in pre-market trading after jumping 123% on Tuesday. Inuvo reported the closing of its earlier announced registered direct offering for total gross proceeds of $8.0 million.
• Hall of Fame Resort & Entertainment Company HOFV rose 28.1% to $2.37 in pre-market trading.
• PCTEL, Inc. PCTI rose 25.7% to $11.16 in pre-market trading after jumping over 35% on Tuesday.
• Avinger, Inc. AVGR rose 21.9% to $2.39 in pre-market trading. Avinger shares jumped over 33% on Tuesday after Aegis Capital raised its price target on the stock from $1 to $2.50. The company last week initiated the commercial launch of its Tigereye image-guided chronic total occlusion crossing system.
• AIkido Pharma Inc. AIKI rose 18.2% to $1.30 in pre-market trading. Alkido Pharma said on January 12, 2021 the company did not obtain approval from stockholders that held a majority of issued and outstanding shares.
• Orbital Energy Group, Inc. OEG rose 17.8% to $4.90 in pre-market trading. Orbital Energy Group reported the closing of its earlier announced registered direct offering.
• AutoWeb, Inc. AUTO shares rose 17.5% to $3.49 in pre-market trading after climbing around 15% on Tuesday.
• Aptorum Group Limited APM rose 16.4% to $3.70 in pre-market trading as the company received Health Canada clearance to initiate Phase 1 clinical trial for ALS-4, a small molecule drug for infections caused by staphylococcus aureus including MRSA.
• VYNE Therapeutics Inc. VYNE shares rose 15.7% to $2.06 in pre-market trading after gaining over 6% on Tuesday.
• Reed's, Inc. REED rose 15.6% to $0.9236 in pre-market trading. Reed's, last week, said it sees preliminary Q4 sales of $10.3 million.
• Novan, Inc. NOVN shares rose 15.2% to $1.51 in pre-market trading. Novan, on Tuesday, announced its B-SIMPLE4 Phase 3 study reached 90% enrollment, with topline data targeted for Q2.
• Sorrento Therapeutics, Inc. SRNE shares rose 15.1% to $10.85 in pre-market trading. Sorrento Therapeutics will be presenting preliminary results from an ongoing SARS-CoV-2 mutation surveillance program for its neutralizing antibodies currently in clinical and pre-clinical development for treatment of patients with COVID-19 disease.
• iClick Interactive Asia Group Limited ICLK rose 15.1% to $16.00 in pre-market trading after climbing 18% on Tuesday.
• BEST Inc. BEST rose 14.6% to $2.35 in pre-market trading.
• TransEnterix, Inc. TRXC shares rose 13.8% to $3.97 in pre-market trading. TransEnterix shares jumped around 69% on Tuesday after the company announced it has received CE Mark approval for the Intelligent Surgical Unit that enables machine vision capabilities on the Senhance Surgical System..
• AMC Entertainment Holdings, Inc. AMC rose 13.1% to $3.46 in pre-market trading. The movie theater company’s stock soared over 31% on Tuesday after it said it raised $100 million through first-lien, secured notes due 2026, as per a filing with the U.S. Securities and Exchange Commission.
• Netflix, Inc. NFLX rose 11.8% to $561.51 in pre-market trading after the company reported better-than-expected Q4 sales and issued strong guidance for the first quarter. Its global streaming paid memberships climbed 21.9% year-over-year to 203.66 million during the quarter. A report also mentioned the company is exploring potential buybacks to return cash to shareholders.
• Isoray, Inc. ISR rose 11.5% to $2.69 in pre-market trading after gaining over 21% on Tuesday. The company, earlier during the month, announced it received FDA 510(k) clearance for the use of C4 Imaging's Sirius positive-signal MRI Markers with Isoray's Cesium-131, brachytherapy seeds.
• CYREN Ltd. CYRN rose 11.5% to $1.54 in pre-market trading after the company announced the availability of its next generation email security solution for Microsoft 365 through the Microsoft Azure Marketplace.
• Predictive Oncology Inc. POAI shares rose 9.6% to $1.14 in pre-market trading. Predictive Oncology, on Tuesday, announced a $2.2 million registered direct offering priced at-the-market.
• Cyren Ltd CYRN rose 8% to $1.49 in pre-market trading after the company announced the availability of its next generation email security solution for Microsoft 365 through the Microsoft Azure Marketplace.
• PACCAR Inc PCAR rose 6% to $94.49 in pre-market trading after the company announced it formed a strategic partnership with Aurora to develop autonomous trucks.

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Check out these big penny stock gainers and losers

Losers

• Document Security Systems, Inc. DSS fell 31% to $3.80 in pre-market trading after the company priced its $24.0 million upsized public offering of common stock.
• BioLineRx Ltd. BLRX shares fell 19% to $2.57 in pre-market trading after the company increased its earlier announced bought deal offering to $30 million.
• Gevo, Inc. GEVO fell 17.4% to $9.11 in pre-market trading as the company reported a 43,750,000 share registered direct common stock offering at $8 per share. Gevo shares jumped 72% on Tuesday after the company co-founder, Frances Arnold, a Nobel-Prize recipient was appointed to President-Elect Joe Biden’s Science Team.
• Histogen Inc. HSTO fell 15.3% to $1.00 in pre-market trading after the company reported the FDA clinical hold for planned Phase 1/2 trial of HST-003 for knee cartilage regeneration.
• AcelRx Pharmaceuticals, Inc. ACRX shares fell 11.1% to $2.09 in pre-market trading after the company announced a common stock offering.
• Riot Blockchain, Inc. RIOT fell 8.4% to $23.08 in pre-market trading. Riot Blockchain, on Tuesday, announced a S19 Pro Antminer fleet expansion.
• CytomX Therapeutics, Inc. CTMX fell 8% to $7.80 in pre-market trading after the company reported a proposed $75 million common stock offering.
• Bionano Genomics, Inc. BNGO fell 7.5% to $8.45 in pre-market trading after the company reported a proposed underwritten public offering of common stock.
• Borr Drilling Limited BORR shares fell 6.9% to $0.9310 in pre-market trading after gaining around 10% on Tuesday.
• Entasis Therapeutics Holdings Inc. ETTX fell 6.8% to $2.75 in pre-market trading after climbing around 12% on Tuesday.
• Foresight Autonomous Holdings Ltd. FRSX fell 6.5% to $9.35 in pre-market trading after surging around 28% on Tuesday.
• Lithium Americas Corp LAC fell 6.1% to $25.18 in pre-market trading after the company announced a proposed public offering of common shares.
• Acer Therapeutics Inc. ACER fell 5.8% to $4.08 in pre-market trading after jumping over 12% on Tuesday.