Gainers
- Cumberland Pharmaceuticals Inc. CPIX rose 117.3% to $4.78 in pre-market trading after the company announced the FDA approved expanded labeling for Caldolor to now include use in pre-operative administration.
- ERYTECH Pharma S.A. ERYP rose 55.3% to $3.72 in pre-market trading after the company secured US patent directed to sequential use of methioninase & asparaginase against solid tumors.
- Pioneer Power Solutions, Inc. PPSI rose 30.6% to $9.97 in pre-market trading after dipping 27% on Monday.
- Allied Healthcare Products, Inc. AHPI rose 29.1% to $9.04 in pre-market trading after dropping more than 15% on Monday.
- Adagene Inc. ADAG rose 15.2% to $9.80 in pre-market trading after the company reported the FDA clearance of IND for Phase 1b/2 trial of anti-CTLA-4 monoclonal antibody ADG116 in combination therapy with anti-PD-1 antibody pembrolizumab.
- Molecular Partners AG MOLN rose 11% to $13.02 in pre-market trading after the company confirmed retained activity of ensovibep on the positions mutated in emerging omicron variant of SARS-CoV-2 in vitro.
- Petros Pharmaceuticals, Inc. PTPI rose 11% to $4.44 in pre-market trading after surging over 91% on Monday.
- Chimerix, Inc. CMRX rose 10.4% to $6.47 in pre-market trading.
- Context Therapeutics Inc. CNTX shares rose 9.3% to $6.10 in pre-market trading after climbing 9% on Monday.
- CTI BioPharma Corp. CTIC rose 9% to $2.90 in pre-market trading after gaining over 7% on Monday.
- BeyondSpring Inc. BYSI rose 8.8% to $14.16 in pre-market trading after tumbling over 9% on Monday.
- iSpecimen Inc. ISPC rose 6.3% to $21.71 in pre-market trading. iSpecimen recently announced it raised $21 million via the sale of stock and warrants.
- Oragenics, Inc. OGEN rose 6.2% to $0.6375 in pre-market trading after gaining more than 9% on Monday.
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Check out these big penny stock gainers and losers
Losers
- AeroClean Technologies, Inc. AERC shares fell 10.5% to $105.00 in pre-market trading after jumping around 45% on Monday.
- Array Technologies, Inc. ARRY fell 10.2% to $20.51 in pre-market trading after the company reported a proposed private offering of $325 million of convertible senior notes.
- cbdMD, Inc. YCBD fell 9.3% to $1.76 in pre-market trading. CbdMD shares jumped 30% on Monday after the company announced a multi-year exclusive agreement with Amify, an Amazon.com platform partner.
- Palatin Technologies, Inc. PTN shares fell 9.1% to $0.7775 in pre-market trading after gaining more than 50% on Monday.
- Valneva SE VALN fell 8.7% to $61.45 in pre-market trading. Valneva shares climbed around 13% on Monday after the company and IDT Biologika announced a collaboration to produce Valneva's inactivated COVID-19 vaccine candidate VLA2001.
- Micro Focus International plc MFGP fell 8.2% to $4.59 in pre-market trading. Micro Focus, earlier during the month, announced it will sell its archiving and risk management portfolio to Smarsh.
- JinkoSolar Holding Co., Ltd. JKS fell 7.3% to $51.90 in pre-market trading after reporting Q3 earnings.
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