Benzinga's Top #PreMarket Losers

Avanir Pharmaceuticals AVNR shares fell 16.32% to $3.59 in the pre-market trading after the company reported that phase II PRIME study of investigation drug AVP-923 did not meet primary efficacy endpoint. The company also reported a wider Q4 loss. Laboratory Corp. of America Holdings LH dipped 7.71% to $91.51 after the company issued a weak 2014 profit guidance. Joy Global JOY shares dropped 4.61% to $53.65 in pre-market trading after the company reported an 87% drop in fiscal fourth-quarter earnings. Icahn Enterprises LP IEP dipped 4.05% to $127.30 in the pre-market session after tumbling 10.68% on Tuesday.