Gainers
- ShiftPixy, Inc. PIXY shares rose 69.9% to $0.7391 in pre-market trading. The company announced the effective date for its reverse stock split after the close. Shareholders voted to approve a reverse split on Aug. 21. After the closing bell on Tuesday, ShiftPixy said the one-for-twenty-four reverse split will take effect on Sept. 30.
- MSP Recovery, Inc. LIFW shares rose 41.7% to $0.2155 in pre-market trading after falling around 25% on Tuesday.
- Cardiff Oncology, Inc. CRDF shares gained 35.8% to $2.20 in pre-market trading after the company announced clinical data in pancreatic cancer and small cell lung cancer, including single-agent activity from onvansertib monotherapy.
- Galecto, Inc. GLTO shares rose 30.2% to $0.7470 in pre-market trading after the company announced plans to explore strategic alternatives.
- AcelRx Pharmaceuticals, Inc. ACRX shares surged 20.8% to $0.6999 in pre-market trading.
- Gaucho Group Holdings, Inc. VINO gained 14.8% to $2.40 in pre-market trading after falling over 12% on Tuesday. Gaucho Group recently announced a 1-for-10 reverse stock split.
- Galmed Pharmaceuticals Ltd. GLMD shares jumped 11.4% to $0.64 in pre-market trading. Galmed Pharmaceuticals recently announced the allowance of a Japanese patent related to treatment of pulmonary and dermal fibrosis.
- Brainstorm Cell Therapeutics Inc. BCLI rose 10.7% to $0.4340 in pre-market trading after falling 8% on Tuesday. The FDA recently said it does not believe there is sufficient evidence to support that any of the assessed biomarkers for the company's ALS therapy is reasonably likely to predict clinical benefit.
- ThermoGenesis Holdings, Inc. THMO rose 9.9% to $1.44 in pre-market trading after gaining around 12% on Tuesday.
- Avalo Therapeutics, Inc. AVTX shares climbed 8.6% to $0.1640 in pre-market trading after falling 7% on Tuesday. Avalo Therapeutics announced the payoff of the remainder of its $35 million debt owed to Horizon Technology Finance.
Losers
- Femasys Inc. FEMY fell 25.7% to $1.10 in pre-market trading. Femasys shares jumped 346% on Tuesday after the company received FDA 510(k) clearance for FemaSeed, an infertility treatment.
- PolyPid Ltd. PYPD fell 25.7% to $4.00 in pre-market trading after declining 4% on Tuesday. PolyPid recently announced a successful Good Manufacturing Practice (GMP) audit by the Israeli Ministry of Health.
- Know Labs, Inc. KNW shares fell 21% to $0.28 in pre-market trading after declining over 20% on Tuesday. Know Labs recently filed for offering of 14,814,815 shares of common stock.
- Minerva Surgical, Inc. UTRS fell 19.3% to $0.2280 in pre-market trading after jumping 55% on Tuesday.
- SIGNA Sports United N.V. SSU shares fell 18.4% to $0.2618 in pre-market trading.
- Tharimmune, Inc. THAR fell 17.4% to $0.2430 in pre-market trading after surging 33% on Tuesday.
- Benson Hill, Inc. BHIL fell 15.3% to $0.32 in pre-market trading.
- Pieris Pharmaceuticals, Inc. PIRS shares fell 14.1% to $0.2630 in pre-market trading after dropping more than 5% on Tuesday.
- Axcella Health Inc. AXLA fell 12.3% to $6.96 in pre-market after declining around 10% on Tuesday.
- Conduit Pharmaceuticals Inc. CDT fell 10.8% to $5.85 in pre-market trading after declining more than 36% on Tuesday.
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